Sant'Antioco is a the name of both an island and a municipality (comune) in southwestern Sardinia, in the Province of Carbonia-Iglesias, in Sulcis zone. With a population of 11,730, the municipality of Sant'Antioco it is the island's largest community. It is also the site of ancient Sulci, considered the second city of Sardinia in antiquity.
* The Palaeo-Christian Basilica of Sant'Antioco, restored in 1089-1102
* Roman bridge
* Ancient akropolis
* Phoenician and Punic necropolises
* Ferruccio Barreca Archaeological Museum
* The Forte Su Pisu (1812)